White to off-white, round (diameter: 11.8 mm), biconvex, uncoated tablets debossed with ‘AR and 400’ separated with breakline on one side and plain on the other side. 4.1 Therapeutic indications. Haemodialysis significantly enhances the removal of aciclovir from the blood and may, therefore, be considered a management option in the event of symptomatic overdose.
Systemic administration of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rabbits, rats or mice.
Pharmaceutical form. Pharmaceutical form. after marrow transplant) or in patients with impaired absorption from the gut the dose can be doubled to 400 mg Aciclovir, or alternatively, intravenous dosing could be considered. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. For the full list of excipients, see section 6.1.
Each Fyris Tablet contains 200 mg or 400 mg of the active ingredient aciclovir.
Aciclovir was not found to be carcinogenic in long term studies in the rat and the mouse. A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to any formulation of Aciclovir. Very rare: Acute renal failure, renal pain.
Dosage titration down to 200 mg Aciclovir taken thrice daily at approximately eight-hourly intervals or even twice daily at approximately twelve-hourly intervals may prove effective.
Systemic administration of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rats, rabbits or mice.In a non-standard test in rats, foetal abnormalities were observed, but only following such high subcutaneous doses that maternal toxicity was produced. For the full list of excipients, see section 6.1.
Accelerated diffuse hair loss.
after marrow transplant) or in patients with impaired absorption from the gut, consideration should be given to intravenous dosing.Dosing should begin as early as possible after the start of an infection: Treatment of herpes zoster yields better results if initiated as soon as possible after the onset of the rash. Aciclovir triphosphate interferes with the viral DNA polymerase and inhibits viral DNA replication with resultant chain termination following its incorporation into the viral DNA. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions.
In addition, adverse events may vary in their incidence depending on the indication. However no dosage adjustment is necessary because of the wide therapeutic index of aciclovir.An experimental study on five male subjects indicates that concomitant therapy with aciclovir increases AUC of totally administered The use of aciclovir should be considered only when the potential benefits outweigh the possibility of unknown risks.
The tablet can be divided into equal doses.
Aciclovir is only partially absorbed from the gut. However no dosage adjustment is necessary because of the wide therapeutic index of aciclovirAn experimental study on five male subjects indicates that concomitant therapy with aciclovir increases AUC of totally administered The use of aciclovir should be considered only when the potential benefits outweigh the possibility of unknown risks. AV-400 (Tablets Aciclovir 400 mg) Nimpact-MD (Tablets Nimsulide 100 mg) MeTop-XL-50 (Capsule Metoprolol Succinate U.S.P 47.50 mg) AV-400 (Tablets Aciclovir 400 mg) ₹ 117.85 ₹ 22.32 Include GST. A detrimental effect on such activities cannot be predicted from the pharmacology of the active substance, but the adverse event profile should be borne in mind.The frequency categories associated with the adverse events below are estimates.
Findings from reproduction toxicology studies are included in Section 5.3.Following oral administration of 200 mg Aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. Acivir 400 MG Tablet DT is an antiviral agent that is used in the treatment of viral infections such as herpes labialis, genital herpes, shingles, chickenpox, etc.
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4.5 Interaction with other medicinal products and other forms of interaction6.6 Special precautions for disposal and other handling9. 4.5 Interaction with other medicinal products and other forms of interaction6.6 Special precautions for disposal and other handling9. caused by herpes zoster and varicella-zoster. In a study of 20 male patients with normal sperm count, oral aciclovir administered at doses of up to 1g per day for up to six months has been shown to have no clinically significant effect on sperm count, motility or morphology.There have been no studies to investigate the effect of aciclovir on driving performance or the ability to operate machinery.
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